Your Choice Therapeutics is working on hormone-free contraception with science developed at UC Berkeley. The startup recently debuted at Y Combinator.
The company debuted at a recent demo day hosted by Silicon Valley tech hubStacked with researchers from UC Berkeley, the startup has published several basic studies in top-notch science journals.When University of California at Berkeley scientists Polina Lishko and Nadja Mannowetz first dreamt up the idea for a new kind of birth control, they didn't intend to create an option for men.
But a few years and several published papers later, and they realized the drug they were creating could be taken by both women and men. At a demo day hosted by Silicon Valley tech hubAlthough their science is still early, Your Choice's team has created the foundation for a hormone-free method that would prevent pregnancy by robbing a man's sperm of the energy it would need to fertilize a woman's egg. Outside experts call the approach"promising.
First, it would prevent hundreds of millions of sperm from swimming to an egg by essentially disabling their main power source — their tails. As an added back-up in case a few crafty sperm find their way to an egg anyway, Your Choice's drug would also disable the drilling action they need to fertilize the egg.
Because it doesn't contain hormones, the drug would also be free from the side effects linked to current hormone-based women's contraceptives. Those side effects include migraine headaches, weight gain, mood swings, and more. And while no male birth control has yet been brought to market, some of the drugs being studied could come with side effects like erectile dysfunction and reduced sex drive.
Your Choice hopes to avoid those side effects by steering clear of hormones and crippling sperm activity instead.
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