For just the second time, a patient with AIDS appears to have been cured after receiving a stem cell transplant from a donor with a genetic mutation. But the mutation is rare, raising controversial questions of whether it may be replicated using nascent gene-editing tools like CRISPR/Cas9.
Share to twitterTimothy Ray Brown poses for a photograph, Monday, March 4, 2019, in Seattle. Brown, also known as the"Berlin patient," was the first person to be cured of HIV infection, more than a decade ago. Now researchers are reporting a second patient has lived 18 months after stopping HIV treatment without sign of the virus following a stem-cell transplant. But such transplants are dangerous, cannot be used widely and have failed in other patients.
The case is the first apparent replication of another in which an American named Timothy Brown - also known as 'the Berlin Patient' - was cleared of AIDS after receiving a stem cell transplant in 2007. Brown reportedly continues to live HIV-free in the United States today.
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