'If diseases happen because of DNA that becomes disorganized with age, we can use research like this to target interventions that can delay cancer and other degenerative diseases,' the study co-author explained
In 18 species of rodents with varying lifespans, researchers looked at sirtuin 6 , a gene which plays a role in processes in the body including aging, cellular stress resistance, and DNA repair.
While animals with relatively short lifespans don’t have so many DSBs, Bohmann explained, “if you want to live for 50 years or so, there’s more of a need to put a system into place to fix these breaks. The SIRT6 protein seems to be the dominant determinant of lifespan. We show that at the cell level, the DNA repair works better, and at the organism level, there is an extended lifespan.”
Gorbunova explained the team pinpointed five amino acids which appear to make the SIRT6 protein stronger and “more active in repairing DNA and better at enzyme functions.” The team will continue their work by studying the SIRT6 of animals with extremely long lifespans, including the bowhead whale which can live for over 200 years.Dr. Vera Gorbunova, Professor of Biology at the University of Rochester, said in a statement: “The ultimate goal is to prevent age-related diseases in humans. If diseases happen because of DNA that becomes disorganized with age, we can use research like this to target interventions that can delay cancer and other degenerative diseases.
इंडिया ताज़ा खबर, इंडिया मुख्य बातें
Similar News:आप इससे मिलती-जुलती खबरें भी पढ़ सकते हैं जिन्हें हमने अन्य समाचार स्रोतों से एकत्र किया है।
Stonehenge was built by descendants of Neolithic migrants, DNA study showsWe may not know exactly how or why Stonehenge was built, but new research affords a glimpse of the people who erected England’s iconic stone monument some 5,000 years ago. - NBCNewsMACH
और पढो »
Perspective | Media must ‘fight their own DNA’ to properly cover the redacted Mueller report.News outlets have to grapple with reporting-while-reading and with political spin flooding the zone.
और पढो »
Two murders stumped cops for 40 years. The key was sitting in a bathroom cabinet.A California whodunit ends after 40 years thanks to new advances in DNA technology.
और पढो »
DNA from old razor helped solve two cases of rape and murder from 40 years agoPolice have cracked a cold case with DNA found on the razor of the man they say raped and killed two women more than four decades ago in California
और पढो »
DNA testing service Ancestry pulls ad said to romanticize slaveryDNA testing service Ancestry pulls ad said to romanticize slavery.
और पढो »
New Genetic 'Score' Can Predict Risk For Obesity, Study SaysImagine what you might do differently if DNA testing from a simple blood test told you there was a strong chance that you –– or your child –– could become overweight or obese.
और पढो »