Opinion: Physicians cured a man of HIV. But that’s not our best shot at fighting AIDS.
A human T cell, in blue, under attack by HIV, in yellow. By Anthony S. Fauci March 11 at 6:39 PM Anthony S. Fauci is director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health.
The cured man, known as the “London patient,” also had Hodgkin’s lymphoma that was unresponsive to chemotherapy. He underwent a stem cell transplantation for his cancer from a donor whom physicians selected for a rare genetic mutation of a cellular receptor called CCR5. This receptor normally allows HIV to bind to certain cells and infect the body — but people with the mutation are resistant to infection with HIV.
Nonetheless, people with HIV must take these drugs for the rest of their lives, as a diabetic would insulin. A cure would alleviate the need for daily medication and reduce the huge economic burden of providing lifelong treatment to tens of millions of people living with HIV around the world.
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